4 doctors weighed in:

What are the affects of nitroprusside used in conjunction with dobutamine?

4 doctors weighed in
Dr. Mark Rasak
Internal Medicine - Cardiology
1 doctor agrees

In brief: Depends on dosing

Dobutamine is an agent that helps the weak heart pump better by stimulating beta receptors in the heart.
At lower doses it doesnt affect the blood vessels but higher doses it can also lower the tone of the ateries and makes it easier for the heart to pump. This tone is aka systemic vascular resistence. By lowering the svr the cariac out put will increase. Nipride (nitroprusside) has no beta stim effects only svr.

In brief: Depends on dosing

Dobutamine is an agent that helps the weak heart pump better by stimulating beta receptors in the heart.
At lower doses it doesnt affect the blood vessels but higher doses it can also lower the tone of the ateries and makes it easier for the heart to pump. This tone is aka systemic vascular resistence. By lowering the svr the cariac out put will increase. Nipride (nitroprusside) has no beta stim effects only svr.
Dr. Mark Rasak
Dr. Mark Rasak
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Dr. Bennett Werner
Internal Medicine - Cardiology

In brief: Vasodilitation

Nitroprusside very potently dilates blood vessels and reduces the workload of the heart.
Dobutamine stimulates cardiac contraction but also constricts blood vessels in a dose dependent fashion which can counteract the nitroprusside effect. The combination has been used to treat cardiogenic shock.

In brief: Vasodilitation

Nitroprusside very potently dilates blood vessels and reduces the workload of the heart.
Dobutamine stimulates cardiac contraction but also constricts blood vessels in a dose dependent fashion which can counteract the nitroprusside effect. The combination has been used to treat cardiogenic shock.
Dr. Bennett Werner
Dr. Bennett Werner
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Dr. Budi Bahureksa
Internal Medicine - Cardiology

In brief: CHF

In the presence of chf, it lowers the blood pressure in the heart itself -- allowing the heart to function easier.

In brief: CHF

In the presence of chf, it lowers the blood pressure in the heart itself -- allowing the heart to function easier.
Dr. Budi Bahureksa
Dr. Budi Bahureksa
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