23 doctors weighed in:

Do omega-3 fatty acids affect blood lipoproteins?

23 doctors weighed in
Dr. Mark Stern
Internal Medicine - Cardiology
12 doctors agree

In brief: They lower trigs

They lower triglycerides.

In brief: They lower trigs

They lower triglycerides.
Dr. Mark Stern
Dr. Mark Stern
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1 comment
Dr. Milton Alvis, jr
Be aware: (1) triglycerides=fat molecules, not lipoproteins, & published research/clinical trials focused on triglycerides, NOT the 5 major classes of lipoproteins which transport all fat molecules. (2) Multiple Omega-3 fatty acids exist & it is only Eicosapentaenoic acid (actually from phytoplankton: only collected from caught fish) which has dominant evidence of ↓ing both Trigs & death rates.
Dr. Milton Alvis, jr
Preventive Medicine
3 doctors agree

In brief: EPA Best Evidence

Both epa ; dha, from phytoplankton, at very high (i.
e. Purified rx) doses, tend to ? the triglyceride concentrations in blood. Epa (without dha ; all the other non-beneficial fats in common fish oil) has a track record of also ?ing LDL particle number, even at lower doses, thus i commonly recommend purified epa. Even more effective for ?ing triglycerides is greatly ?ing all carb foods ; ?obesity.

In brief: EPA Best Evidence

Both epa ; dha, from phytoplankton, at very high (i.
e. Purified rx) doses, tend to ? the triglyceride concentrations in blood. Epa (without dha ; all the other non-beneficial fats in common fish oil) has a track record of also ?ing LDL particle number, even at lower doses, thus i commonly recommend purified epa. Even more effective for ?ing triglycerides is greatly ?ing all carb foods ; ?obesity.
Dr. Milton Alvis, jr
Dr. Milton Alvis, jr
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Dr. Michael Shapiro
Internal Medicine - Cardiology
2 doctors agree

In brief: Many ways

At common doses (1g epa/dha) of fish oil there are not major changes in lipids/lipoproteins.
However, at higher doses (2-4g epa/dha), tirglycerides may be decreased by 30-50% and while ldl-c may staty the same or increase, LDL particle number (ldl-p) stays the same or decreases.

In brief: Many ways

At common doses (1g epa/dha) of fish oil there are not major changes in lipids/lipoproteins.
However, at higher doses (2-4g epa/dha), tirglycerides may be decreased by 30-50% and while ldl-c may staty the same or increase, LDL particle number (ldl-p) stays the same or decreases.
Dr. Michael Shapiro
Dr. Michael Shapiro
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Dr. Katharine Garnier
Family Medicine
2 doctors agree

In brief: Several actions

Omege 3 fish oils are most helpful in lowering triglycerides, some people have genetically high triglycerides, and they can also be high for people who are diabetic.
Triglycerides are a different type of fat than cholesterol, that is an independent risk for heart problems, and possibly pancreatitis if they are really high. Fish oil can dramatically reduce them, and may also mildly lower your ldl.

In brief: Several actions

Omege 3 fish oils are most helpful in lowering triglycerides, some people have genetically high triglycerides, and they can also be high for people who are diabetic.
Triglycerides are a different type of fat than cholesterol, that is an independent risk for heart problems, and possibly pancreatitis if they are really high. Fish oil can dramatically reduce them, and may also mildly lower your ldl.
Dr. Katharine Garnier
Dr. Katharine Garnier
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Dr. James Underberg
Internal Medicine

In brief: FishOils Lower Trigs

Omega3 fatty acids at high doses (2-4 gms/day) do lower tg's, but are most effective when the tg'sare elevated >500mg/dl.
At this level they can lower tg's up to 45%. The effect is seen with fish based omega3's (epa & dha) not plant based (eg. Flax seed oil). There is a dose response seen. For each gram of 03's, about 10% additional reduction in triglycerides. Fish burp can be a side effect.

In brief: FishOils Lower Trigs

Omega3 fatty acids at high doses (2-4 gms/day) do lower tg's, but are most effective when the tg'sare elevated >500mg/dl.
At this level they can lower tg's up to 45%. The effect is seen with fish based omega3's (epa & dha) not plant based (eg. Flax seed oil). There is a dose response seen. For each gram of 03's, about 10% additional reduction in triglycerides. Fish burp can be a side effect.
Dr. James Underberg
Dr. James Underberg
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