Plaque build up. It is hardening of the arteries, caused by fat, cholesterol, and other substances building up in the arteries - this is called plaque - making the arteries stiffer. This plaque interferes with the normal function of the arteries and can cause problems and symptoms throughout the body. The plaque can block the arteries and/or it can break off and flow to smaller vessels and block them.
Disease, Artery Wall. Atherosclerosis results from an accumulation of white blood cells, mostly macrophages (called monocytes, one of 5 white blood cell types), which have invaded into the walls of the blood vessel to remove low density lipoprotein (fat carrying protein) particles. The macrophages may die if overwhelmed with LDL & cannot export the ingested fat into high density lipoprotein particles.
Pathogenesis. Refers to the cause or mechanism.
Correct: Mechanism. Amended answer only because the linked illustration did not relate to pathogenesis but to only one organ. Atherosclerosis is a body wide process affecting all arteries. The most well established pathogenesis mechanism, at a cellular level, for over the last half-century are the lipoproteins, the protein particles which transport all fat molecules within the water outside cells.
Atherosclerosis. Atherosclerosis is a life long disease. It is generally at different stages at the same time in various vessels. For this reason taking care of diet, exercise and drug therapy to stop progression of the disease is crucial. Some areas won't be as helped as others but you may stop them from getting worse or at least slow the process down.
One's own. Native coronary means the arteries of that person. There are generally three major vessels. Atherosclerosis is the term for plaque buildup and obstruction of the blood vessel. This is the process which leads to heart attacks.
Arterial narrowing. Plaque build up within the blood vessel supplying blood flow to the heart.