Is it safe to take pyridoxine while pregnant or breastfeeding?

Yes. Pyridoxine, or vitamin b6, is not only safe to take, but it is an important component of your prenatal vitamin make-up. Pyridoxine is crucial to the construction of red blood cells, along with other metabolic functions.
Depends on the dose. Would stay within rda guidelines to be safe unless recommended otherwise by a healthcare professional.