8 doctors weighed in:

Is lung cancer passed down in families?

8 doctors weighed in
Dr. David Cooke
Surgery - Thoracic
4 doctors agree

In brief: Some Types

There is growing evidence that some types of lung cancer can be genetically inherited.
These are types of adenocarcinoma that are linked to genetic mutations in a protein called egfr. Often these lung cancers manifest in younger people who are never smokers.

In brief: Some Types

There is growing evidence that some types of lung cancer can be genetically inherited.
These are types of adenocarcinoma that are linked to genetic mutations in a protein called egfr. Often these lung cancers manifest in younger people who are never smokers.
Dr. David Cooke
Dr. David Cooke
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Dr. Ritesh Rathore
Internal Medicine - Hematology & Oncology
1 doctor agrees

In brief: Risk is increased

A family history increases the risk of lung cancer in individuals upto 2 times.
Individuals with a family history may develop lung cancer as their body cells may be less able to cope with carcinogens such as those found in cigarette smoke, etc.

In brief: Risk is increased

A family history increases the risk of lung cancer in individuals upto 2 times.
Individuals with a family history may develop lung cancer as their body cells may be less able to cope with carcinogens such as those found in cigarette smoke, etc.
Dr. Ritesh Rathore
Dr. Ritesh Rathore
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1 comment
Dr. Michael Thompson
In a family history of cancer there are 1) genetic risks (predisposition to develop cancer) and 2) shared environmental risk (eg, smoking or second hand smoke).
Dr. Maulik Shah
Clinical Genetics

In brief: Possibly

EGFR mutations are somatic meaning they occur within the tumor and can be used for targeted treatment but are not inherited and not associated with susceptibility.
Lung cancer susceptibility in families can be associated with a number of familial cancer syndromes and also with inherited mutations in the genes LNCR1 and LNCR3. There are also genetic syndromes that impair immune functiion

In brief: Possibly

EGFR mutations are somatic meaning they occur within the tumor and can be used for targeted treatment but are not inherited and not associated with susceptibility.
Lung cancer susceptibility in families can be associated with a number of familial cancer syndromes and also with inherited mutations in the genes LNCR1 and LNCR3. There are also genetic syndromes that impair immune functiion
Dr. Maulik Shah
Dr. Maulik Shah
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