6 doctors weighed in:
What's the difference between celexa and wellbutrin (bupropion)?
6 doctors weighed in

Dr. Leonard Spishakoff
Addiction Medicine
3 doctors agree
In brief: Mechanism of action
Celexa (citalopram ) is a antidepressant that works mainly on the serotonin metabolism wellbutrin (bupropion) works in the dopaminergic circuit .
They can be combined for added effect or decrease of side effects of serotonin related antidepressants such as decresed libido.

In brief: Mechanism of action
Celexa (citalopram ) is a antidepressant that works mainly on the serotonin metabolism wellbutrin (bupropion) works in the dopaminergic circuit .
They can be combined for added effect or decrease of side effects of serotonin related antidepressants such as decresed libido.
Dr. Leonard Spishakoff
Dr. Leonard Spishakoff
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Dr. Alan Ali
Psychiatry
2 doctors agree
In brief: Celexa/Wellbutrin
Both are antidepressants.
Celexa is a Serotonin reuptake inhibitor used for major depression & anxiety. Wellbutrin (bupropion) is a separate group of antidepressants with more stimulating effects, used more for anergic depression & sometimes to boost treatment of Attention deficit.

In brief: Celexa/Wellbutrin
Both are antidepressants.
Celexa is a Serotonin reuptake inhibitor used for major depression & anxiety. Wellbutrin (bupropion) is a separate group of antidepressants with more stimulating effects, used more for anergic depression & sometimes to boost treatment of Attention deficit.
Dr. Alan Ali
Dr. Alan Ali
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Dr. Barbara Srur
Psychiatry
2 doctors agree
In brief: Effect on the brain
There are 3 main neurotransmitters in the brain.
Celexa mainly affects the serotonin circuits. Wellbutrin (bupropion) affects the norepinephrine and Dopamine circuits. Depending on the symptoms, one or other , sometimes both of the medications would be chosen. A psychiatrist is the most knowledgable to make the best selection of treatment.

In brief: Effect on the brain
There are 3 main neurotransmitters in the brain.
Celexa mainly affects the serotonin circuits. Wellbutrin (bupropion) affects the norepinephrine and Dopamine circuits. Depending on the symptoms, one or other , sometimes both of the medications would be chosen. A psychiatrist is the most knowledgable to make the best selection of treatment.
Dr. Barbara Srur
Dr. Barbara Srur
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