What effects can bipolar disorder have on a person's body over time? Short and long term effects

Indirect. Bipolar itself as no known direct effects on the body. But indirectly, both manic and depressive episodes can affect health. For example, in the manic phase appetite is suppressed and risk taking (with drugs, sex, dangerous actions) is high. Suicide is a great risk, as well. Appetite can be lost in depression, as well. There are tantalizing genetic overlaps with asthma and endometriosis.