Could you give me the median survival for the elderly, over 65, with acute lymphoblastic leukemia? Also, what was it 30 yrs. Ago? I lost a loved one in 1982, wondering if life expectancy improving in this age group? I'm not sure what the life expectancy w

Not too good... Age older than 60 years is one of the adverse prognostic indicators for adult acute lymphoblastic leukemia. The presence of the philadelphia chromosome, mll gene rearrangement, WBC over 100, 000/microliter, and failure to achieve remission after 4 weeks of therapy are other poor prognostic factors. Overall, only 20-40% of adults are cured and these are usually the ones without adverse factors.
Modern . Modern therapy is expected to get 60 - 80% of adults with all into remission. Unfortunately, with standard chemotherapy alone only 30-40% of adult all patients live more than 2 years. This likely compares to a 20-30% long-term survival rate in the early 1980s. Much more significant improvements have been made in the treatment of children with all with long-term survival in over 80% of kids with the disease. We now know much more about the genetic abnormalities in the cancer cells than we did in the 1980's and can better predict a patient's prognosis and tailor treatment for them. In particular, outcomes are now much better for mature b-cell all and there are targeted agents available for treating philadelphia chromosome-positive disease as well. Age continues to be a poor prognostic factor with people over 50 not fairing as well as younger adult patients.

Related Questions

Dear doctor, could you give me the median survival in early 80, s for elderly acute lymphoblastic leukemia, ? I I am having difficulty finding these statistics. Are we making any progress in the elderly with this type of leukemia? Thanks in advance.

ALL. Unfortunately the survival for elderly patients with all is limited due to the intensity of the therapy needed. Patients with philadelphia chromosome positive disease may respond well to tyrosine kinase inhibitors. Without further details it is difficult to answer thus question but the survival average is generally less than 1 year for somebody in their 80's. Read more...
Not too good... Age older than 60 years is one of the adverse prognostic indicators for adult acute lymphoblastic leukemia. The presence of the philadelphia chromosome, mll gene rearrangement, WBC over 100, 000/microliter, and failure to achieve remission after 4 weeks of therapy are other poor prognostic factors. Overall, only 20-40% of adults are cured and these are usually the ones without adverse factors. Read more...

Whats the expected survival rate in a 19 male with (all) acute lymphoblastic leukemia?

Need more info. Prognosis in all is still very good in young adults when treated with aggressive chemotherapy (and possibly radiation). One of the most powerful prognostic features is cytogenetics (e.g. Philadelphia chromosome, mll, and tel/aml1). T versus b cell, CNS involvement, response to initial chemo, all give additional information. Read more...

Hi please give me any information u know about alternative acute lymphoblastic leukemia treatment in mexico?

Unknown. I would strongly suggest not using alternative treatments outside the country if your disease has not been previously treated. There is no published data suggesting that alternative therapies are advantageous. Speak with your physician prior to embarking on any such alternative treatment. Consider speaking with cancer centers of america for additional treatment ideas. Read more...
They do not work... Unfortunately alternative medicines do not work in leukemia, or other cancers for that matter. There are many doctors and other "health care providers" that offer alternative treatment to cancer patients, many times in other countries to side-step laws protecting patients. I would be very wary of these treatments. Most are out to make money, not help patients. Read more...
Cruel scams. Forgive me. These fake clinics have been around for decades. These people prey on the vain hopes and fears of people in crisis. The proprietors claim to be persecuted geniuses and humanitarians. When the Rx's fail, they'll blame you. ("If only you hadn't eaten junk food.") They bring money into Mexico so the government tolerates them. Would you go there to buy anything else of real value? Read more...

What are the chances of my child getting a secondary cancer after her leukemia treatment is completed? Daughter, age 9, treated for acute lymphoblastic leukemia, no radiation, 2.5 years of intrathecal and oral chemo meds.

A . A paper published by the national cancer institute in 2007 looked at secondary malignancy rates in over 16, 000 kids diagnosed and successfully treated for leukemia and lymphoma. Overall, the rate of a second cancer in kids treated for leukemia (not specifying what kind of leukemia or treatment) within 30 years after diagnosis was 2.4%. The chance of developing cancer in the general (adult and kid) population is 0.6%. In this study, most secondary cancers occurred in kids that were treated for leukemia between the ages of 1 and 4 years of age. The other thing to consider is that they were looking at patients treated in the late 1970's and 1980's and treatments may have changed since then. The good news is that your daughter has a lot of things going for her such as her age, the type of leukemia she had (usually very treatable with less toxic medications than other cancers), and the fact that she did not have radiation. So her risk might be even less than the other kids in that study. If you have any specific questions about her care, please talk with her oncologist. I hope she stays happy and healthy! (odds are she will.) legal disclaimer: I am providing this general and basic information as a public service and my response to this question does not constitute a doctor-patient relationship. For any additional information, advice, or specific concerns, please speak with your own physician. The information provided is current as of the date of the answer entry. Read more...
Secondary Cancers. The literature suggests that successfully treated all patients, who did not have radiotherapy, are at no increased risk for secondary cancers. With radiation, the risk has been cited as as much as 20-fold. Read more...

Can I get acute lymphoblastic leukemia, without having a spleen?

Yes. There is no relation to the presence of a spleen and the development of leukemia. Leukemia can cause an enlarged spleen, but not having a spleen will not keep you from getting leukemia. Read more...

Could you tell me about acute lymphoblastic leukemia in children?

See below. It is a blood cancer in children. With advances in the treatment the prognosis has improved quite a bit. It used to be universally fatal disease about 15 years ago but now most children survive and get cured. Read more...
See below... The most common type of cancer in childhood is leukemia. The most common pediatric leukemia is acute lymphoblastic leukemia, more specifically b-all. The patient needs to be in the care of a pediatric oncologist. The prognosis depends on many factors, one of the most important ones being the genetic abnormality, but is many times very good in children with cure rates at about 80-90%, even higher. Read more...

I've got all or acute lymphoblastic leukemia. How can an adult get a childhood cancer?

Adults get it too. While acute lymphoblastic leukemia (all) is the most common cancer in children, adults get it also. In fact, more adults each year are diagnosed with all than children. It is usually more difficult to treat when it occurs in adults compared to children. Read more...

My white blood cell count was 365000 when I was diagnosed with acute lymphoblastic leukemia (2012), how long would I have lived without treatment?

Can't know answer. This is difficult to say with certainty. Patients that have wbc's as high as yours are critically ill at the time of diagnosis. Factors that would influence how long someone like you would survive without therapy include how fast the WBC (and leukemia cell burden) is increasing, whether there was infection present, and whether complications of dic or tumor lysis was present. In summary, not long. Read more...
Not long. Hope you get a long-term cure, and glad it was picked up. The acute leukemias are chaotic systems and it's impossible to predict when death may come. The actual white count is immaterial, while a very low platelet count may result in a fatal hemorrhage at an unpredictable time and organ involvement unrelated to lab values can do the same. Read more...

I have a child with acute lymphoblastic leukemia?

ALL. I'm sorry to here about your child with all. Do you have a question? The cure rate of all has improved dramatically over the years and is one of the success stories in oncology fsupporting the rationale of continued research and iterative improvements in care. Read more...
Question please?? I'm sure you are under tremendous stress and have a million concerns. The next year is going to be very intense and require someone to be a 24 hour a day caretaker. There will be hospitalizations, procedures, pain and tears. The great news is that most types of ALL are now curable if you follow the oncologist's care plan exactly. Please ask friends, family, any support people to help out!! Read more...