4 doctors weighed in:

What is the difference between stage and grade for brain cancer?

4 doctors weighed in
Dr. Nader Pouratian
Neurosurgery
1 doctor agrees

In brief: Grade is key.

Brain tumors are rated by the world health organization grade, with higher grades generally being more aggressive.
Stage is a terminology used in cancers outside of the brain, which describe how much a cancer has spread all over the body. Because brain tumors/cancers generally do not spread all over the body, we rarely use "staging" with primary brain tumors.

In brief: Grade is key.

Brain tumors are rated by the world health organization grade, with higher grades generally being more aggressive.
Stage is a terminology used in cancers outside of the brain, which describe how much a cancer has spread all over the body. Because brain tumors/cancers generally do not spread all over the body, we rarely use "staging" with primary brain tumors.
Dr. Nader Pouratian
Dr. Nader Pouratian
Thank
Dr. Andrew Turrisi
Radiation Oncology

In brief: Primary brain

Tumors in adults never metastasize, and the grade determines prognosis, time of survival, or time to recurrence.
The grade + stage, but commonly low grade is stage i, ii including astrocytoma, oligoastrocytoma. Anaplastic astro: grade 3; glioblastoma, is stage iv.

In brief: Primary brain

Tumors in adults never metastasize, and the grade determines prognosis, time of survival, or time to recurrence.
The grade + stage, but commonly low grade is stage i, ii including astrocytoma, oligoastrocytoma. Anaplastic astro: grade 3; glioblastoma, is stage iv.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
1 comment
Dr. Walter Klein
I agree with you except that I would not say never metastasize in adult. It happpens but is extremely rare (I have seen it a few times as a pathologist) as most patients die beforehand.
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