4 doctors weighed in:

Is isoniazid-rifampin safe for women who are pregnant or breastfeeding?

4 doctors weighed in
1 doctor agrees

In brief: No

Isoniazid-rifampin has not been formally assigned to a pregnancy categoy by the fda.
Isoniazid-rifampin is only recommended for use during pregnancy when benefit outweighs risk. Both of them have been assigned to a pregnancy category c by the fda. There are no controlled data in human pregnancy; however, both of them known to cross the placental barrier and appear in a cord blood. No bf recommen.

In brief: No

Isoniazid-rifampin has not been formally assigned to a pregnancy categoy by the fda.
Isoniazid-rifampin is only recommended for use during pregnancy when benefit outweighs risk. Both of them have been assigned to a pregnancy category c by the fda. There are no controlled data in human pregnancy; however, both of them known to cross the placental barrier and appear in a cord blood. No bf recommen.
Dr. Ecaterina Sartina
Dr. Ecaterina Sartina
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Dr. R. Wayne Inzer
Obstetrics & Gynecology
1 doctor agrees

In brief: No

Both drugs are category c, which means there are no direct human harm shown, but animal studies show adverse effects on the fetus.
The benefits may outweigh the risks, under certain circumstances, this should be discussed with your doctor. Rifampin is considered safe with breast feeding while Isoniazid is not and may decrease flow and quality of milk.

In brief: No

Both drugs are category c, which means there are no direct human harm shown, but animal studies show adverse effects on the fetus.
The benefits may outweigh the risks, under certain circumstances, this should be discussed with your doctor. Rifampin is considered safe with breast feeding while Isoniazid is not and may decrease flow and quality of milk.
Dr. R. Wayne Inzer
Dr. R. Wayne Inzer
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