6 doctors weighed in:

What would be a good way to cure down syndrome? What would be a way to remove the extra chromosome from every cell in the body? I need a good idea. Thanks :)

6 doctors weighed in
Dr. William Singer
Pediatrics - Neurology
1 doctor agrees

In brief: No cure

Unfortunately there is no cure for down syndrome.
there is research ging on looking ito the possiblity of inactivating one of the three 21 chromosomes, but it is in early stages and it is not known what the outcome would be from doing so

In brief: No cure

Unfortunately there is no cure for down syndrome.
there is research ging on looking ito the possiblity of inactivating one of the three 21 chromosomes, but it is in early stages and it is not known what the outcome would be from doing so
Dr. William Singer
Dr. William Singer
Thank
Dr. Andrius Baskys
Psychiatry - Geriatric
1 doctor agrees

In brief: It

It is true that there is no such treatment today that would allow to remove an extra chromosome from every single cell in the body.
However, for someone who is looking for ideas, there are several to explore. One idea would be to use antisense oligonucleotides to reduce expression of certain genes in the additional chromosome. This approach has been gaining momentum lately and there are already two or more antisense oligonucleotide-based drugs that have been approved by fda. An example of genes that could be targeted with antisense in down's syndrome could be the gene responsible for the amyloid production. It is known that patients with down's syndrome develop significant amyloid deposits early in their lives. These deposits (they are also found in alzheimer's disease brains) impact overall function and quality of life of these patients. One could expect that reducing amyloid deposits related to the extra chromosome could improve their quality of life. There are many sources of information on antisense oligonucleotide technology and wikipedia is one of them.

In brief: It

It is true that there is no such treatment today that would allow to remove an extra chromosome from every single cell in the body.
However, for someone who is looking for ideas, there are several to explore. One idea would be to use antisense oligonucleotides to reduce expression of certain genes in the additional chromosome. This approach has been gaining momentum lately and there are already two or more antisense oligonucleotide-based drugs that have been approved by fda. An example of genes that could be targeted with antisense in down's syndrome could be the gene responsible for the amyloid production. It is known that patients with down's syndrome develop significant amyloid deposits early in their lives. These deposits (they are also found in alzheimer's disease brains) impact overall function and quality of life of these patients. One could expect that reducing amyloid deposits related to the extra chromosome could improve their quality of life. There are many sources of information on antisense oligonucleotide technology and wikipedia is one of them.
Dr. Andrius Baskys
Dr. Andrius Baskys
Thank
Dr. James Ferguson
Pediatrics

In brief: Realism works

It is nice to imagine that technology or research could somehow undo something that happens naturally.
It is good to have hope, but we are not there now. At best you can provide the best medical care for any DS associated problems. You can work to maximize their learning and opportunities.You can assist them in avoiding those that would take advantage of them.

In brief: Realism works

It is nice to imagine that technology or research could somehow undo something that happens naturally.
It is good to have hope, but we are not there now. At best you can provide the best medical care for any DS associated problems. You can work to maximize their learning and opportunities.You can assist them in avoiding those that would take advantage of them.
Dr. James Ferguson
Dr. James Ferguson
Thank
Dr. Laura McMullen
Pediatrics

In brief: There

There is no cure for down syndrome and no way that anyone knows of to affect the chromosomes of every cell in the body.

In brief: There

There is no cure for down syndrome and no way that anyone knows of to affect the chromosomes of every cell in the body.
Dr. Laura McMullen
Dr. Laura McMullen
Thank
Get help from a real doctor now
Dr. Jonathan Jassey
Board Certified, Pediatrics
13 years in practice
1M people helped
Continue
108,000 doctors available
Read more answers from doctors