My 66 yrs old husband has swelled red hands that have blistered and cracked open. He has done nothing unusual or new he has been soaking them and wrapping them with gauze because of the oozing they are painful and itchy

He . He may have hand dermatitis, also known as eczema. Typically this creates red, scaly, cracked, and sometimes fissured hands and fingers. I would see a dermatologist who can possibly prescribe a topical steroid cream and other medication to help improve this. It is also important to get looked at because other skin conditions can present this way such as psoriasis, fungal infections, etc.