How does avastin (bevacizumab) affect male fertility?

It doesn't (so far) Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf.
Not sure. Cholesterol-lowering agents can reduce the ability to build new membranes and sperm need lots of new membranes. Having said this, a definitive relationship between cholesterol lowering agents and male infertility has not been described.

Related Questions

Does avastin (bevacizumab) reduce male fertility?

No (so far) Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf.
Probably not. There are many cholesterol-lowering agents that are fda approved and they all appear safe (at least as far as we know) for male fertility.
Bevacizumab. Avastin (bevacizumab) is a brand of Bevacizumab which is used to fight cancer. In that sense, you've got bigger fish to fry. Regardless, thinking long-term, I checked out http://www. Drugs. Com/avastin. Html and https://online. Epocrates. Com and found concern for ovarian failure but no mention of testicular issues or male fertility concerns. Best to discuss w/your oncologist. Perhaps bank your sperm before chemo.

What effect does avastin (bevacizumab) have on male fertility?

Unsure. Avastin (bevacizumab) has shown to be deterimental to female reporuductive potential with up to 30-35% have serious complications (ovarian failure). To my knowledge there are no studies on men. Any chemotherapy has the potential risk of causing fertility issues in the future. You may want to consider freezing sperm with a sperm bank or your local reproductive endocrinologist. Also talk to your oncologist.

What affect does avastin (bevacizumab) have on fertility?

Possible menopause. Avastin (bevacizumab) is used to treat certain advanced cancers. It may cause ovarian failure (induced menopause), up to 34 percent of women in one study. However, this will reverse in 1/5 of women once Avastin is stopped.