What is a safe way to treat shingles during pregnancy?

Valtrex (valacyclovir) for 7 days. Shingles is when dormant chickenpox virus reactivates and causes painful blisters on limited areas of your skin. It will often appear with pregnancy and other immunocompromised states. Shingles is not dangerous to your unborn baby. The best treatment is oral valtrex (valacyclovir) for seven days. Valtrex is a prescription drug and is felt to be safe to take in pregnancy.