7 doctors weighed in:

What causes cleft palate in a baby?

7 doctors weighed in
Dr. Dinh Bui
Dentistry
2 doctors agree

In brief: Familial,environment

Multifactorial with genetic and environmental factors play major roles.
Cleft lip, with or without cleft palate, are due to a failure of fusion of the medial nasal, lateral nasal, and maxillary processes on one or both side. Isolated clefts of the secondary palate are due to failure of palatal shelves to fuse. Must distinguished between isolated deformities or part of a syndrome.

In brief: Familial,environment

Multifactorial with genetic and environmental factors play major roles.
Cleft lip, with or without cleft palate, are due to a failure of fusion of the medial nasal, lateral nasal, and maxillary processes on one or both side. Isolated clefts of the secondary palate are due to failure of palatal shelves to fuse. Must distinguished between isolated deformities or part of a syndrome.
Dr. Dinh Bui
Dr. Dinh Bui
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Dr. Richard Ruden
Dentistry
2 doctors agree

In brief: Genetic factors

Cleft lip and cleft palate occur when tissues in the baby's face and mouth don't form properly.
Normally, the tissues that make up the lip and palate fuse together in the second and third months of pregnancy. But in babies with cleft lip and cleft palate, the fusion never takes place or occurs only partially, leaving an opening (cleft).

In brief: Genetic factors

Cleft lip and cleft palate occur when tissues in the baby's face and mouth don't form properly.
Normally, the tissues that make up the lip and palate fuse together in the second and third months of pregnancy. But in babies with cleft lip and cleft palate, the fusion never takes place or occurs only partially, leaving an opening (cleft).
Dr. Richard Ruden
Dr. Richard Ruden
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Dr. James Ferguson
Pediatrics

In brief: Specifics unknown

The palate is derived from 3 separate tissue sources that begin to grow toward each other is it forms.
If these ridges fail to fuse the cleft is formed. This is all complete or not by 9-12 wks. There are some genetic factors involved but inheritance not straightforward. A CP mom has 4% risk of having a CP baby while a CP mom & dad together have an 8% risk.

In brief: Specifics unknown

The palate is derived from 3 separate tissue sources that begin to grow toward each other is it forms.
If these ridges fail to fuse the cleft is formed. This is all complete or not by 9-12 wks. There are some genetic factors involved but inheritance not straightforward. A CP mom has 4% risk of having a CP baby while a CP mom & dad together have an 8% risk.
Dr. James Ferguson
Dr. James Ferguson
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