1 doctor weighed in:
What is the genetic reason for causing kleinfelter's?
1 doctor weighed in

Dr. Golder Wilson
Clinical Genetics
In brief: Extra X in men
Klinefelter syndrome is usually caused by an extra x chromosome in males, changing their normal 46, xy chromosome constitution to 47, xxy.
The extra x causes tall stature with an asthenic build, underdevelopment of the testis and infertility. Sometimes there is more than one x, like 48, xxxy, often causing intellectual disability. The extra chromosome is a chance occurrence.

In brief: Extra X in men
Klinefelter syndrome is usually caused by an extra x chromosome in males, changing their normal 46, xy chromosome constitution to 47, xxy.
The extra x causes tall stature with an asthenic build, underdevelopment of the testis and infertility. Sometimes there is more than one x, like 48, xxxy, often causing intellectual disability. The extra chromosome is a chance occurrence.
Dr. Golder Wilson
Dr. Golder Wilson
Thank
Get help from a real doctor now
Dr. Cindy Juster
Board Certified, Pediatrics
32 years in practice
2M people helped
Continue
108,000 doctors available
Read more answers from doctors