4 doctors weighed in:

The karyotype of my cousin shows two barr bodies per cell. What condition might he have?

4 doctors weighed in
Dr. Claude Parola
Internal Medicine
3 doctors agree

In brief: Trisomy-x

According to lyon hypothesis, mammalian species with multiple x chromosomes will have all x's inactivated except one; normally women have xx genotype thus has only one inactivated x ( barr body), men have xy thus has no inactivated x ( no barr body), your cousin most likely has a karyotype of 47, xxx, thus two barr bodies, so called " super woman", most are normal but a few may have problems.

In brief: Trisomy-x

According to lyon hypothesis, mammalian species with multiple x chromosomes will have all x's inactivated except one; normally women have xx genotype thus has only one inactivated x ( barr body), men have xy thus has no inactivated x ( no barr body), your cousin most likely has a karyotype of 47, xxx, thus two barr bodies, so called " super woman", most are normal but a few may have problems.
Dr. Claude Parola
Dr. Claude Parola
Thank
Get help from a real doctor now
Dr. Vicken Poochikian
Board Certified, Internal Medicine
38 years in practice
2M people helped
Continue
108,000 doctors available
Read more answers from doctors