8 doctors weighed in:

My sister has a son with hemophilia, but there is no family history other than that, is this just bad luck?

8 doctors weighed in
Dr. Ankush Bansal
Internal Medicine
4 doctors agree

In brief: Perhaps

Hemophilia a & b are x-linked recessive while c is usually autosomal recessive.
So, it's possible that the mother was a carrier. However, about 1/3 of a & b cases are due to spontaneous mutation.

In brief: Perhaps

Hemophilia a & b are x-linked recessive while c is usually autosomal recessive.
So, it's possible that the mother was a carrier. However, about 1/3 of a & b cases are due to spontaneous mutation.
Dr. Ankush Bansal
Dr. Ankush Bansal
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Dr. Steven Neish
Pediatrics - Cardiology
2 doctors agree

In brief: Spontaneous mutation

About a third of the cases of the two most common causes of hemophilia are due to spontaneous mutations.

In brief: Spontaneous mutation

About a third of the cases of the two most common causes of hemophilia are due to spontaneous mutations.
Dr. Steven Neish
Dr. Steven Neish
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1 comment
Dr. Carlos Encarnacion
True. Also remember that this is a recessive, X-linked condition so if there is a predominance of women your family, it may not be evident.
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