7 doctors weighed in:
If someone in your family has down syndrome, is there a larger risk that your baby will have down syndrome?
7 doctors weighed in

Dr. Ira Salafsky
Clinical Genetics
4 doctors agree
In brief: Slight risk
Most down syndrome is sporadic.
A few patients with down syndrome have the extra 21 chromosome translocated on to another chromosome. In some of these cases the parents can carry the translocated chromosome in a balanced form and they and other family members could be at increased risk to have children with the syndrome.

In brief: Slight risk
Most down syndrome is sporadic.
A few patients with down syndrome have the extra 21 chromosome translocated on to another chromosome. In some of these cases the parents can carry the translocated chromosome in a balanced form and they and other family members could be at increased risk to have children with the syndrome.
Dr. Ira Salafsky
Dr. Ira Salafsky
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Dr. Richard Roberts
Clinical Genetics
1 doctor agrees
In brief: Yes
A clinical geneticist will inform you that your empiric risk is approximately 1 in 100 because of the history, so prenatal diagnosis is indicated.
A revolution has occurred over the past year. Maternal blood for free fetal DNA analysis, with 99.99 % accuracy, from 9w0d or10w0d, results in 7-10 days for trisomies 21, 13, and 18. For people without insurance, one company charges $25--150.

In brief: Yes
A clinical geneticist will inform you that your empiric risk is approximately 1 in 100 because of the history, so prenatal diagnosis is indicated.
A revolution has occurred over the past year. Maternal blood for free fetal DNA analysis, with 99.99 % accuracy, from 9w0d or10w0d, results in 7-10 days for trisomies 21, 13, and 18. For people without insurance, one company charges $25--150.
Dr. Richard Roberts
Dr. Richard Roberts
Thank
Dr. William Singer
Pediatrics - Neurology
1 doctor agrees
In brief: Downs syndrome risk
In general, downs syndrome does not run in families.
Risks appear to relate to maternal age at the time of pregnancy.

In brief: Downs syndrome risk
In general, downs syndrome does not run in families.
Risks appear to relate to maternal age at the time of pregnancy.
Dr. William Singer
Dr. William Singer
Thank
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