2 doctors weighed in:
If my brother had a child with immunodeficiency at birth, should I get tested to see if my children will have it?
2 doctors weighed in

Dr. Nayla Mumneh
Internal Medicine - Allergy & Immunology
In brief: No
It all depends on the type of immunodeficiency but most infant immunodeficiencies are secondary to a mutation.
Do other members of the family suffer from the same? If so, yes you all need to be tested. Your question is best answered by a genetic counselor.

In brief: No
It all depends on the type of immunodeficiency but most infant immunodeficiencies are secondary to a mutation.
Do other members of the family suffer from the same? If so, yes you all need to be tested. Your question is best answered by a genetic counselor.
Dr. Nayla Mumneh
Dr. Nayla Mumneh
Thank
Dr. Javier Chinen
Pediatrics - Allergy & Asthma
In brief: Depends on diagnosis
Chances of having children with a genetic condition depend on the specific genetic diagnosis.
If the immunodeficient child was a boy, and the condition is x-linked, (gene defective is in chromsome x), then it is highly unlikely that the father has a similar gene defect. In all other scenarios most specific diagnosis is necessary for further counseling.

In brief: Depends on diagnosis
Chances of having children with a genetic condition depend on the specific genetic diagnosis.
If the immunodeficient child was a boy, and the condition is x-linked, (gene defective is in chromsome x), then it is highly unlikely that the father has a similar gene defect. In all other scenarios most specific diagnosis is necessary for further counseling.
Dr. Javier Chinen
Dr. Javier Chinen
Thank
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