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How often is prenatal screening wrong?

1 doctor weighed in
Dr. Golder Wilson
Clinical Genetics

In brief: Often if quad screen

Maternal serum screening with three (triple test) or quad (four markers), when combined with ultrasound (integrated screen) will detect about 88% of fetuses with down syndrome--however, there are many false positives (abnormal when fetus is normal) and even more false negatives (normal screen when fetus has down syndrome or another chromosome aberration.

In brief: Often if quad screen

Maternal serum screening with three (triple test) or quad (four markers), when combined with ultrasound (integrated screen) will detect about 88% of fetuses with down syndrome--however, there are many false positives (abnormal when fetus is normal) and even more false negatives (normal screen when fetus has down syndrome or another chromosome aberration.
Dr. Golder Wilson
Dr. Golder Wilson
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