3 doctors weighed in:

How accurate is the genetic testing for ovarian cancer?

3 doctors weighed in
Dr. Golder Wilson
Clinical Genetics
1 doctor agrees

In brief: Very if BRCA mutated

The genes brca1 and brca2 cause breast-ovarian cancer, suspected when women have onset of breast cancer before menopause or when there are several cases of breast/ovarian cancer in a family.
Women with a brca mutation have as much as a 50% lifetime risk for ovarian cancer (85% for breast) and often choose prophylactic oophorectomy after positive brca testing since there is no good clinical screen.

In brief: Very if BRCA mutated

The genes brca1 and brca2 cause breast-ovarian cancer, suspected when women have onset of breast cancer before menopause or when there are several cases of breast/ovarian cancer in a family.
Women with a brca mutation have as much as a 50% lifetime risk for ovarian cancer (85% for breast) and often choose prophylactic oophorectomy after positive brca testing since there is no good clinical screen.
Dr. Golder Wilson
Dr. Golder Wilson
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In brief: Depends

If you test positive for a known mutation, you have an increased lifetime risk of ovarian cancer, 40% for brca and 12% for lynch syndrome.
If you test negative for a mutation for which a family member with ovarian cancer was positive, then your risk is not increased. If you test negative but have a strong family history, you are still at increased risk due to other genes not tested.

In brief: Depends

If you test positive for a known mutation, you have an increased lifetime risk of ovarian cancer, 40% for brca and 12% for lynch syndrome.
If you test negative for a mutation for which a family member with ovarian cancer was positive, then your risk is not increased. If you test negative but have a strong family history, you are still at increased risk due to other genes not tested.
Dr. Katherine Sutherland
Dr. Katherine Sutherland
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