11 doctors weighed in:
Can a chiari malformation type one be picked up in an amniocentesis test?
11 doctors weighed in

Dr. Golder Wilson
Clinical Genetics
5 doctors agree
In brief: No
Chiari malformation is associated with many conditions, some of which have abnormal chromosomes that would show up by amniocentesis.
The malformation itself can be seen by fetal ultrasound but not usually at 16-18 weeks when visualization of fetal anomalies might prompt recommendation for amniocentesis.

In brief: No
Chiari malformation is associated with many conditions, some of which have abnormal chromosomes that would show up by amniocentesis.
The malformation itself can be seen by fetal ultrasound but not usually at 16-18 weeks when visualization of fetal anomalies might prompt recommendation for amniocentesis.
Dr. Golder Wilson
Dr. Golder Wilson
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Dr. Ken Yonemura
Neurosurgery
2 doctors agree
In brief: No
Amniocentesis will be positive if the nervous system is malformed and exposed to the spinal fluid.
A chiari type 1 abnormality means that the cerebellar tonsils are sitting below the exit point of the skull called the craniocervical junction. The brain and spinal cord are otherwise normal and as a result the amiocentesis will be normal for a chiari type 1.

In brief: No
Amniocentesis will be positive if the nervous system is malformed and exposed to the spinal fluid.
A chiari type 1 abnormality means that the cerebellar tonsils are sitting below the exit point of the skull called the craniocervical junction. The brain and spinal cord are otherwise normal and as a result the amiocentesis will be normal for a chiari type 1.
Dr. Ken Yonemura
Dr. Ken Yonemura
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Dr. Georgianne Snowden
Radiology - Interventional
2 doctors agree
In brief: NO
Only open neural tube defects (spina bifida as an example) cause the level of Alpha fetal protein to be elevated on amniocentesis.

In brief: NO
Only open neural tube defects (spina bifida as an example) cause the level of Alpha fetal protein to be elevated on amniocentesis.
Dr. Georgianne Snowden
Dr. Georgianne Snowden
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