Does oil glands destroyed by Accutane gets restored after a while?

Isotretinoin . Isotretinoin (accutane, clarivis, sotret) changes the function of sebaceous (oil) glands, but does not destroy them. Dry skin from Isotretinoin can be prolonged, particularly when you have the additive effects of dry winter weather. Moisturize as needed, but use non-comedogenic (won't clog pores) lotions.