How is narcolepsy and REM sleep related?

Closely. The symptoms of narcolepsy are those of parts of rem sleep intruding into wakefulness. These elements include sleepiness; hallucinations (dream imagery) while falling asleep or waking up; and cataplexy and sleep paralysis (both from the normal muscle paralysis that occurs during rem sleep).
Very Connected. Rem sleep refers to rapid eye movement sleep, a very different type of sleep than non-rem. In patients with narcolepsy, a certain neurotransmitter called hypocretin is deficient. Hypocretin is pa powerful wake promoter and stabilizes sleep/wake stability. So less hypocretin can result in inappropriate rem sleep to intrude into wakefullness.
Very Connected. Rem sleep refers to rapid eye movement sleep, a very different type of sleep than non-rem. In patients with narcolepsy, a certain neurotransmitter called hypocretin is deficient. Hypocretin is pa powerful wake promoter and stabilizes sleep/wake stability. So less hypocretin can result in inappropriate rem sleep to intrude into wakefullness.

Related Questions

Is it possible to have a narcolepsy diagnosis in a patient who never had REM sleep during an mslt's naps?

Maybe. The international classification of sleep disorders has specific criteria which must be met to diagnose someone with narcolepsy. As part of these criteria, you need to have 2 or more episodes of sleep onset-rems during the mslt. However, if the spinal fluid level of hypocretin is low, you can also make the diagnosis. But, you can have excessive daytime sleepiness that is not narcolepsy. Read more...
Yes. Other reasons may occur for no rem. If person with cataplexy they do not need this test for absolute diagnosis. If patient on medications that suppress rem that could be another cause. Read more...

Is there any harmful side effects of interrupting REM sleep?

Yes. Delta phase of the sleep cycle is the deepest level of sleep in which hgh is released. Interrupted rem sleep prevents moving into deeper levels of delta phase in which the restorative aspects are at play. Read more...

What is the most effective OTC brand for getting a restful, full REM sleep that doesn't leave you feeling groggy in the am?

.bestsleepaids.org. www.bestsleepaids.org. This is not a scientific review, rather a consumer-rated opinion. The product contains melatonin, valerian root, hops, lemon balm, phenibut, 5-htp, l-theanine. It is said to increase stages 3 and 4 sleep ( now referred to as stage n3 sleep) and increase rem sleep as well. And the winner in 2013 consumer award is ...., ..., ...........Somnamax. Read more...

Had polysomnography. Please explain: increase in phasic motor activity w/o stereotypical behaviors seen during REM sleep.?

Jump around. in sleep. This needs to be interpreted in the context of all the other brain findings of the sleep study. by itself it isn't all that important and doesn't indicate much except a potential problem for interrupted sleep. especially for the person next to you. Read more...