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What is the differrence between cortisol and cortisone ?!

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In brief: Similar

Both are steroid hormones.
Cortisol is the more "powerful" of the two, accounting for about 95% of the glucocorticoid activity in the body. Cortisone is a metabolite of cortisone, but it has much less of an effect. It can be considered an inactive form of cortisol, although cortisone can be converted into cortisol if needed.

In brief: Similar

Both are steroid hormones.
Cortisol is the more "powerful" of the two, accounting for about 95% of the glucocorticoid activity in the body. Cortisone is a metabolite of cortisone, but it has much less of an effect. It can be considered an inactive form of cortisol, although cortisone can be converted into cortisol if needed.
Dr. David Hettinger
Dr. David Hettinger
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