What is the best OTC pain medicine for a sprained knee?

Knee sprain. Nonsteroidal anti-inflammatory drugs (NSAIDS) can help with both pain relief and in reducing inflammation. Examples are ibuprofen (like Advil, Nuprin or Motrin), Naproxen sodium (like Aleve, (naproxen) Naprosyn, Anaprox) or Asprin (such as Bayer, Ecotrin, Ascriptin). Avoid NSAID's if pregnant or allergic to them. In that situation can consider acetaminophen.
Ibuprofen or similar. Nonsteroidal anti-inflammatories, such as Ibuprofen are best for sprains. Icing the knee intermittently can also help, while elevation may help keep swelling down.
NSAIDs . Try motrin, ibuprofen, Naproxen with food and as long as you don't have gastritis or stomach problems.Ice, elevation and rest helps as well. Tylenol (acetaminophen) if stomach problems, kidney or heart problems.
Magnesium salicylate. Support the sprained area with local muscle rub and ace wrap herb horsetail extract also helps to repair tendons.

Related Questions

What's the best treatment for a mild knee sprain and slight inflammation on the inner side?

"R.I.C.E." Sprains are best treated with rest, ice, compression, and elevation. Inner knee pain can be a sign of a mcl (medial collateral ligament) sprain, which tends to do well with conservative non-surgical care. Persistent pain can be a sign of a torn medial meniscus, the shock absorber of the knee, so any knee pain lasting more than a month to 6 weeks should be checked out with an orthopedic surgeon. Read more...
Treatment: Ice for 20 minutes, three to four times per day. You could wear a hinged knee brace for support. Only use crutches if you really need to. Take an over the counter anti-inflammatory if you can. Read more...