I'm on aspirin for my heart problem. Can I take tylenol (acetaminophen) for headache?

YES. If you have to take the tyelnol more than weekly for your headache; see your doctor to find out the cause of the headache. Tylenol (acetaminophen) is removed by the liver so make sure you don't have liver problems or other medications that may interact with the tylenol (acetaminophen) or cause problems for the liver in combination. Your doctor should be able to help you identify potential problems.