My wife rita midha serum vitd3 is143mcg (normal value is up to 55mcg is having symtoms of toxicity like loss of apetite, gastritis & nerveous system.?

Stop any supps, CMD. Hard to get that level of vitamin d without excess supplements-won't get it from sunlight, foods (other than eating polar bear liver-mistake early explorers made, eskimos knew better). Stop any and all supplements, or sources of vitamin d in diet; see doc re: meds to see if any are liver toxic. See doc, d excess can cause liver toxicity as well.