3 doctors weighed in:

If i'm allergic to sulfa will i be allergic to codeine?

3 doctors weighed in
Dr. Martin Ostro
Internal Medicine - Allergy & Immunology
1 doctor agrees

In brief: Probably not.

Sulfa allergy doesn't increase likelihood of allergy to other meds.
Most reactions to Codeine not allergic but side-effects of codeine/narcotics (gi upset, constipiation, sedation, itching, hives). Codeine directly causes histamine release without the participation of allergic antibodies. Also, sulfa allergy is only to sulfa antibiotics, not other types of sulfas, e.G diurectics, diabetes meds.

In brief: Probably not.

Sulfa allergy doesn't increase likelihood of allergy to other meds.
Most reactions to Codeine not allergic but side-effects of codeine/narcotics (gi upset, constipiation, sedation, itching, hives). Codeine directly causes histamine release without the participation of allergic antibodies. Also, sulfa allergy is only to sulfa antibiotics, not other types of sulfas, e.G diurectics, diabetes meds.
Thank
Dr. Larry Lutwick
Internal Medicine - Infectious Disease

In brief: No

There is an cross reactivity between the sulfonamide group of antimicrobials and codeine.

In brief: No

There is an cross reactivity between the sulfonamide group of antimicrobials and codeine.
Thank