When is tamoxifen for breast cancer treatment?

Chemotherapy. Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention").
See below. Tamoxifen can be used after other treaments such as surgery, radiation and chemotherapy to prevent a cancer recurrence, or it can be used if cancer has spread in order to slow it's growth.

Related Questions

Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Small risk. Tamoxifen is asociated with a small (less than 5%) risk of uterine cancers, women on tamoxifen require regular gynecologic checkups every 6-12 months and high-risk women may need ultrasound screeenings too. Read more...
Possible but rare. Uterine wall thickening is a known side effect of tam. It usually presents as abnormal spotting or bleeding. Definitive DX is via endometrial biopsy. If ignored it can progress to uterine cancer. This is usually cured with hysterectomy alone. Read more...

Does taking tamoxifen for breast cancer treatment cause cancer of the uterus?

Yes. Tamoxifen has been shown to increase the risk of uterine cancer, not unlike estrogen replacement therapy, with an incidence of ~1:500. However, this is almost-always caught at its earliest stage, with very high cure rates. If you compare the benefit of tamoxifen for either treating or preventing breast cancer compared to this risk, the benefit far outweighs the risk. Read more...
Tamoxifen. If you get vaginal bleeding, you need a biopsy of the endometrium. Some doctors do ultrasounds looking for polips as well . Read more...

Can taking tamoxifen for breast cancer treatment induce cancer of the uterus?

Maybe. There is a slight increased risk of endometrial cancer of 1 in 500 chance reported. The benefits of tamoxifen in treatment of breast cancer is much higher than the risk of endometrial cancer. Ask your oncologist and ob-gyn how best to follow or watch for this potential risk. Read more...

Does taking tamoxifen for breast cancer treatment induce development of cancer of the uterus?

It can. Studies show that women who take tamoxifen have twice the risk of uterine cancer as compared to non treated patients. However, the benefits of tamoxifen for the treatment of breast cancer far outweigh the risks. Aromatase inhibitors are a group of drugs that can be used instead of tamoxifen for post-menopausal breast cancer patients; these drugs do not have this risk. Read more...
Yes. The chance is about 1% and treatment is hysterectomy. With such a low chance then tamoxifen is worth the risk. A gynecologist needs to keep track of the patient and any unusual bleeding evaluated. There are also other hormone alternatives with less risk. Check with your medical oncologist to see which drug is best for a particular patient. Read more...

Is tamoxifen a must for er/pr negative menstruating woman for breast cancer treatment?

No. Actually, it's er/pr positive women who are potential candidates for tamoxifen. This is advised for women whose cancer stage mandates chemotherapy, sometimes combined with traditional IV chemotherapy. Furthermore, we often recommend tamoxifen to prevent the development of a second cancer is breast cancer survivors. Read more...
No. This and similar medicines are anti Estrogens that block the receptors. So if the patient has negative receptors there is little benefit from the medication. So it's not a must. Read more...

Is it okay for an oncologist to do breast cancer treatment without tamoxifen?

Yes. Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. It has no role in rx of estrogen (-) breast ca. Furthermore, aromatase inhibitors are an effective alternative to tamoxifen for estrogen (+) breast cancer after menopause. Read more...
Yes! Tamoxifen is only useful in breast cancers which are estrogen receptor positive(er+). So tamoxifen is of no use if the tumor is er negative. Check your tumor's hormone receptor status and you will have the answer to your question>. Read more...

What happens during a breast cancer treatment?

Breast Cancer Cure. If you had lumpectomy and adjuvant chemotherapy and radiation therapy will have almost 80% cure rate. If you tumor was quite large you should have neoadjuvant chemotherapy to reduce the tumor size before surgery. The surgical oncologist will decide if you can have lumpectomy or mastectomy. Adjuvant radiation therapy will be given after lumpectomy. If tumor is her 2 positive will need herceptin (trastuzumab). Read more...
Treatment of Breast. During breast cancer chemotherapy treatment, there are long list of possible side effects, nausea, vomiting, diarrhea, abdominal pain, low white blood cell counts with possible fever which might need admission to hospital. Patient will also have hair loss. Also they may have low red blood cells counts, low platelets which may need blood transfusion, platelet transfusion as necessary. Read more...
Breast cancer tx. During a breast cancer treatment, you would work closely with your oncology team- including a breast surgeon, medical oncologist and radiation oncologist. All of them will work with you so you can get the best therapy available tailored to your case and to ensure that you can get through the therapy well, cope with those possible adverse events and still able to maintain descent quality of life. Read more...

What are the side-effects of breast cancer treatment?

Breast cancer is treated with surgery, radiation and chemotherapy. Side effects of surgery are related to removal of lymph nodes. This can cause lymphedema, but only in about 1/3 of patients. The chemotherapy can cause numbness, aka neuropathy, and the radiation can cause scarring of the skin. Overall the side effects of therapy are considered mild compared to untreated cancer which can be fatal. Read more...
Depends on treatment. This is a complex question. Each treatment-surgery, radiation, chemo, hormonal- has it's own uniques set of side effects. In addition, not everyone will experience side effects. The good news is that most side effects can be managed with treatment or medications. Be sure to ask your oncology team questions. Read more...

What are common proven alternatives to chemotherapy for breast cancer treatment?

Alternative to what? Chemotherapy is the administration of a drug that circulates throughout the body and kills cancer cells. Our goal is to choose the most effective drug tailored to one's specific cancer subtype. If by "alternative" you mean alternative to proven, standard therapy...No. However, many of our "standard" drugs are well-tolerated w/o traditional side-effects like hair loss, nausea, etc. Read more...