3 doctors weighed in:

Is there a specific blood test to diagnose pernicious anemia? I have a family history. My doctor told me I have borderline B12 deficiency.

3 doctors weighed in
Dr. Jon Fishburn
Ophthalmology
2 doctors agree

In brief: Pernicious anemia

Yes your doctor can run a battery of tests including a cbc, peripheral blood smear, a serum b 12 level, and a reticulocyte count.
These usually will help to diagnose the condition. Sometimes methylmalonic acid and homocysteine levels will be drawn to help with the diagnosis.

In brief: Pernicious anemia

Yes your doctor can run a battery of tests including a cbc, peripheral blood smear, a serum b 12 level, and a reticulocyte count.
These usually will help to diagnose the condition. Sometimes methylmalonic acid and homocysteine levels will be drawn to help with the diagnosis.
Dr. Jon Fishburn
Dr. Jon Fishburn
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1 comment
Dr. Gurmukh Singh
Auto-antiboidies to stomach are a consistent feature of classical pernicious anemia, in addition tot the tests mentioned by Dr. Fishburn.
Dr. Arthur Heller
Internal Medicine - Gastroenterology
1 doctor agrees

In brief: Antiparietal cell

Not all B12 deficiency is due to pernicious anemia-autoimmune disease, antiparietal cell and antiintrinsic factor antibodies.
Other rtests may be needed to check for, e.g. H pylori infection.

In brief: Antiparietal cell

Not all B12 deficiency is due to pernicious anemia-autoimmune disease, antiparietal cell and antiintrinsic factor antibodies.
Other rtests may be needed to check for, e.g. H pylori infection.
Dr. Arthur Heller
Dr. Arthur Heller
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