How does vagus nerve stimulation therapy work exactly?

VNS. Vagus nerve stimulation is a neuromodulation system that provides constant electrical stimulation of the vagus nerve in the neck. It is indicated for epilepsy and depression. The exact mechanism of action is unknown.
For what? It's is well known that vagal stimulus may lower the heart rate (useful in tachycardias)lowers the production of acid in the stomach (vagotomy surgery for peptic ulcers) and also can suddenly stop hiccups. Maneuvers that stimulate the vagus (could be dangerouse): massaging carotid bulb in the neck, putting pressure to the eyeballs, putting pressure to the forehead, gag reflex, valsalva.
Vagal Nerve Stim. Works by modulating activity of the Nucleus Solitarius in the brain stem. Pulsatile electrical impulses are delivered from a signal generator implanted under the skin to the left Vagus Nerve. The frequency and strength of the signal is adjusted to maximise seizure control, mood, attention and other parameters over time. If you want more detail feel free to ask www. Healthtap. Com/drericweisman.

Related Questions

What can vagus nerve stimulation therapy do for epilepsy?

Prevent seizures. Vagus nerve stimulation (vns) is designed to prevent seizures by sending regular, mild pulses of electrical energy to the brain via the vagus nerve. These pulses are supplied by a device something like a pacemaker. Http://www. Epilepsy. Com/epilepsy/vns.
Like a medication. Vns units are valuable, and do improve seizure control over time, without medication adverse effects, but not really too much more successful than many medications (aed's). However, if more than 2 or 3 medications are not helpful, and if surgery not an option, vns may be game-changing.

What percentage of epilepsy patients are good candidates for vagus nerve stimulation (vns) therapy?

VNS candidates. Must be at least 12 years old (in the US) and have seizures that are known to respond to VNS (eg. Focal seizures, secondarily generalized seizures) and have failed to achieve adequate seizure control with at least two anticonvulsants (with documented therapeutic levels) or a combination of medications. Typically they are not good epilepsy surgery candidates. In my practice: about 1/3 patients.

What about vagus nerve stimulation as a treatment for chronic depression?

Lukewarm option. Vagal nerve stimulation (vns) for treatment resistant depression is fda approved (2005). However, subsequent studies have not been too supportive of its use. There are many medication options and combinations these days as well as transcranial magnetic stimulation (less invasive) and electroconvulsive therapy (still an effective treatment).

What is the definition or description of: vagus nerve stimulation?

Epilepsy. The vns unit is designed to stimulate the vagus nerve, which effects the locus coeruleus, and in turn over a period of time, decreases the frequency of complex partial seizures. Used when meds no longer the answer, but acts similar to an anti-epileptic drug, just without some of the adverse effects. Probably works best after a few years, and must be implanted surgically.
Seizure Treatment. Vagus nerve stimulation involves the surgical implantation of a small device, similar to a pacemaker, in the chest with wires under the skin which are wrapped around the vagus nerve in the neck. Vns has been found effective in the treatment of some patients with seizures.
VNS. Is a type of highly successful neuromodulation therapy for refractory seizures and depression. In the future VNS therapy will be used for CHF and likely other conditions. Tiny electrical impulses are delivered to the Vagus Nerve in the neck to modulate brainstem activity in the case of VNS for seizures and depression.

Can you tell me about an operation called vagus nerve stimulation?

Straightforwards. To install this device to control epilepsy, the surgeon inserts a small stimulator device over the left upper chest wall, then connects to the left vagal nerve, and closes, a process of about 25-40 minutes. The device is turned on and initially programmed 2 weeks post-op, and is fully programmed over about 3-4 months.

How effective is vagus nerve stimulation?

VNS for Depression. Vns is an fda- approved invasive procedure for treatment resistant depression. Vns can take months to see results, and has a response rate of 22-30% and a remission rate of about 15-17%.

I am undergoing vagus nerve stimulation, what happens if a seizure occurs while asleep?

VNS. Units are set for on and off periods, and are not 100 % perfect, even when optimally programmed. A magnet is included, and if swiped across the vns device, will cause it to fire, and perhaps stop the seizure. If you sleep with a partner, the other can stop the seizure activity, but, if you sleep alone, the seizure will likely complete, but maybe the unit will decrease frequency well over time.

What is vagus nerve stimulation?

Depression treatment. A form of treatment where small electrical pulses are applied to your vagus nerve in your neck as it travels to your brain. It is used for certain types of epilepsy and depression which is refractory to antidepressants.
Seizure Treatment. Vagus nerve stimulation involves the surgical implantation of a small device, similar to a pacemaker, in the chest with wires under the skin which are wrapped around the vagus nerve in the neck. Vns has been found effective in the treatment of some patients with seizures.