It depends on...
Etiology, location and anatomy.
I agree with dr. Pak's answer, but the mainstay of definitive treatment of lower extremity varicosities is currently endovenous ablation
to treat an underlying source of reflux
when identified. This can be followed by ambulatory phlebectomy/sclerotherapy
to treat remaining varicosities. Ultrasound evaluation needs to be performed early: dont wait for skin changes