Most Likely. Mefenamic acid is used to relieve mild to moderate pain, including menstrual pain. Mefenamic acid is in a class of medications called nsaids. It works by stopping the body's production of a substance that causes pain, fever, and inflammation. If you have no problems with nsaids and flaring of your asthma, then you are safe to try it. Have u ever taken aleve, (naproxen) motrin, aspirin, ibuprofen?