Lump under skin on wrist thumb side purple over veins on wrist and down thumb was this a clot took an aspirin lump went down but left large bruise?

Get that checked out. This sounds like a thrombosed (clotted) vein in your hand. The Aspirin may have helped to dissolve the clot. This could happen for several reasons. It also could be something else. I would get this checked out just be cautious.