3 doctors weighed in:

Can endometrial cancer be treated with megace (megestrol)?

3 doctors weighed in
Dr. John Geisler
Gynecology - Oncology

In brief: Endometrial cancer

It depends upon the type and grade of cancer.
Megace (megestrol) is often used for people to sick to have surgery, people trying to preserve fertility, and for recurrence.

In brief: Endometrial cancer

It depends upon the type and grade of cancer.
Megace (megestrol) is often used for people to sick to have surgery, people trying to preserve fertility, and for recurrence.
Dr. John Geisler
Dr. John Geisler
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Dr. Morton Levitt
Pathology

In brief: Megace (megestrol) Treatment

Megace (megestrol) has been used as an adjunct to treat advanced endometrial cancer, in addition to primary treatment protocols.
The precise mechanism of its antineoplastic effect is unknown, but presumably , it decreases estrogen levels in the body by interacting with the pituitary gonadal axis, and estrogen is known to stimulate some sub types of sensitive endometrial cancer cells.

In brief: Megace (megestrol) Treatment

Megace (megestrol) has been used as an adjunct to treat advanced endometrial cancer, in addition to primary treatment protocols.
The precise mechanism of its antineoplastic effect is unknown, but presumably , it decreases estrogen levels in the body by interacting with the pituitary gonadal axis, and estrogen is known to stimulate some sub types of sensitive endometrial cancer cells.
Dr. Morton Levitt
Dr. Morton Levitt
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Dr. Ritesh Rathore
Internal Medicine - Hematology & Oncology

In brief: Yes

Hormonal therapy (including megace (megestrol), (megestrol) tamoxifen) can be used in the treatment of certain endometrial cancers which have recurred or spread to other sites.
Patients with tumors positive for the Progesterone receptor especially may respond to megace (megestrol).

In brief: Yes

Hormonal therapy (including megace (megestrol), (megestrol) tamoxifen) can be used in the treatment of certain endometrial cancers which have recurred or spread to other sites.
Patients with tumors positive for the Progesterone receptor especially may respond to megace (megestrol).
Dr. Ritesh Rathore
Dr. Ritesh Rathore
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