Which of the new Coumadin (warfarin) substitutes are recommended for long term DVT management (and possibly off label as well)?

Xarelto. Xarelto (rivaroxaban) is one of the new anticoagulants that can be used to treat dvt. Go to www.Xalero.Com for more information.
Novel anticoagulants. Keep in mind is that the novel oral anticoagulants (also called target specific oral anticoagulants) do not behave anything like coumadin (warfarin). They are small molecules that reversibly bind to either FXa or FIIa in the coagulation cascade. They have rapid and predictable pharmacokinetics and do not require routine monitoring. The FDA has approved both rivaroxaban and dabigatran for DVT management. .