2 doctors weighed in:

I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

2 doctors weighed in
Dr. Ramachandran Srinivasan
Internal Medicine - Rheumatology

In brief: Polyarteritis nodosa

Diagnosis made by symptoms and findings which may include elevated wbc, ESR , CRP and in some positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients .
Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied . At times biopsy is targeted for affected tissues.

In brief: Polyarteritis nodosa

Diagnosis made by symptoms and findings which may include elevated wbc, ESR , CRP and in some positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients .
Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied . At times biopsy is targeted for affected tissues.
Dr. Ramachandran Srinivasan
Dr. Ramachandran Srinivasan
Thank
Dr. John Goldman
Internal Medicine - Rheumatology

In brief: It could be

It depends on what was biopsied.
Sometimes an angiogram is indicated. There is no specific blood test for pan. If an initial biopsy was done and is negative, sometimes a second biopsy is necessary. Your physician is able to guide you.

In brief: It could be

It depends on what was biopsied.
Sometimes an angiogram is indicated. There is no specific blood test for pan. If an initial biopsy was done and is negative, sometimes a second biopsy is necessary. Your physician is able to guide you.
Dr. John Goldman
Dr. John Goldman
Thank
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