I have lupus, painful interstitial cystitis, and lots of GI issues. Is it worth trying gluten free diet for a while though my celiac test was negative?

Absolutely. Also consider casein free (avoid cow dairy). Must go gluten free for at least 3-6 months for an adequate trial. Casein can cross react and look like gluten. Celiac testing is not accurate. Consider probiotics such as kombucha and kefir (water or goats milk). Can make both yourself at home.
No harm in trying. Other than the expense, but gluten free diet is not likely to be of use if you are not sensitive to gluten.

Related Questions

My lab result showed mild celiac disease should I start a gluten free diet or am I ok. Do I need to see a gi?

It depends, see belo. Trying a gluten free diet is not that hard to do and may make you feel much better. There are a spectrum of symptoms in people with gluten intolerance that result from the auto-immune response to gluten. Eliminating it from the diet stops all the adverse changes and the sooner the better. Wheat, barley, rye are the main grains that contain gluten. Read more...

Test positive for celiacs if you have been on a gluten free diet for 2 months? Is it worth it to go back on gluten to get a positive test result?

No. Your celiac problem is not going to go away so why would you want to make yourself sick again? Remember that some people may not totally recover until after several months off gluten product. However if your symptoms do not improve after 3 or 4 months, you need to evaluate the diagnosis or consider another diagnosis since the presence of celiac does not preclude other illnesses. Read more...