Is Marfan syndrome preventable?

Sometimes. Marfan syndrome is preventable when the adults who know they have marfan syndrome thoughtfully choose not to have biological children (50% of their children would have the disease). Some cases are not preventable, such as the 20-30% of marfan syndrome persons who have the disease from a new mutation (neither parent had a mutation).

Related Questions

What is Marfan syndrome?

Genetic disorder. Of connective tissue that affects many bodily systems.The national marfan foundation has a very nice website that will answer any questions you have about marfan syndrome. Go to www.Marfan.Org. Read more...

What is Marfan syndrome?

Marfans/ehler danlos. Marfan syndrome is a connective tissue disorder, tissues that strengthen bodies structures. In most cases it is inherited condition, but approx 30% of patients have no family history tall arms and height, affects lungs, heart and aorta, eyes causing cataract, skin problems, and tissue covering the spinal chord. Read more...

What causes Marfan syndrome?

Genetic mutation. Marfan syndrome is caused by a gene mutation (in the fbn1 gene). A mutation leads to defective, weakened connective tissue throughout the body. Symptoms show up in the parts of the body where shape and structural integrity relies a lot on the weakened type of connective tissue. Read more...
Fibrillin mutation. Classic marfan syndrome is an autosomal dominant disease caused by a mutation in the fbn1 gene which codes for fibrillin-1, a component of connective tissue. Most people with marfan syndrome have an affected parent, but about 25% of marfan syndrome is caused by a spontaneous mutation of the fbn1 gene. Read more...

What exactly is Marfan syndrome?

Genetic disorder. Fbn1 gene controls connective tissue metabolism. If there are mutations or repeats, then marfa's will result. The symptoms are the result of malformed collagen. So dislocated lens in eye, heart valve problems, scoliosis, pneumothorax, artery problems may occur. Most cases are inherited, but occasionally marfan's occurs from a spontaneous mutation. This gene can be tested for in a blood specimen. Read more...

Does Marfan syndrome skip generations?

No, but. . . Marfan synd. Doesn't skip generations, but sometimes it's mild enough that the person who seemed to have skipped the disease actually had a mild case of it. Also, it is possible that a child of a marfan synd. Parent doesn't inherit the mutation (child is normal), but that child's child or grandchild gets a new mutation or marries a mild, undiagnosed marfan patient... Leading to future marfan kids. Read more...
Thanks for asking! Marfan syndrome is a dominant genetic trait, meaning that people who inherit only one copy of the marfan fbn1 gene from either parent will develop marfan syndrome and be able to transmit it to their children. Read more...

What chromosome is affected by Marfan syndrome?

Chromosome 15. Marfan syndrome is caused by a mutation in the fbn1 gene on chromosome 15. The "address" for this gene is 15q21.1. This gene codes for a protein called fibrillin-1. Inheritance is autosomal dominant. Read more...

Can patients with mild Marfan syndrome build body?

Yes, but... Marfan as you know designates that you have very loose joints and hyperextensibility. Unfortunately this same flexibility may also apply to your heart valves or large blood vessel--the aorta--just outside the main pumping chamber of your heart. Therefore, you should receive clearance from your cardiologist before doing any serious weight lifting or resistance training traditional for body building. Read more...