There are many different types of scoliosis braces.
Some are worn only at night. Some are worn day and night. Some are made with hard plastic on the outside and soft foam on the inside while others are made to be "flexible". In order for a brace to be effective, it has to correct the curve so there is some "pressure" or "squeezing" sensation. Most people get used to it over the first 2-4 wks.