Can you explain a punnet square of sickle cell anemia?

In 400 words? This sounds like homework. This is simple mendelian genetics, the old 1:2:1 ratio of outcomes if two carriers mate. So if two sickle carriers mate, 1/4 offspring will be wild-type, 2/4 will be carriers, and 1/4 will have full-blown sickle cell disease. http://www.ndsu.edu/pubweb/~mcclean/plsc431/mendel/mendel1.htm.
Sickle cell anemia. It is just impossible to explain sickle cell anemia in 400 words. It is a genetic blood disorder that is inherited from the parents. The disorder is due to point mutation of the b-globin chain of the hemoglobin -that makes the red blood cells more sensitive and can make them sickling towards exposure of dfferent eg. Infection, dehydration etc.It may lead to acute and chronic complication & death.

Related Questions

What is sickle cell anemia?

Hereditary. Sickle cell anemia is a hereditary condition where some of the red blood cells become sickle shaped and rigid, and can't get through the smallest capillaries. Blocked circulation causes extreme pain in joints, abdomen, or chest. Read more...
Its a severe anemia. A form of anemia that affects many people around the world. It results from a defective form of hemoglobin in the red cells, that results in deformation (sickling) and destruction of red cells, as well as blockage of small capillary vessels causing pain in bones, lung problems, possible strokes, severe fatigue and a shortened lifespan. It is inherited, but you need 2 defective genes from mom n dad. Read more...

Is sickle cell anemia painful?

Pain crisis=painful. Sickle cell anemia itself is not painful . However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis ( this is painful), or other episode such as acute chest syndrome , stroke etc. Read more...

Can I have sickle cell anemia?

Anyone can... It would be unlikely that would could reach the age of 46 and not be diagnosed with sickle cell anemia. If you are truly concerned, testing is very easy. Read more...

Is sickle cell anemia hereditary?

Yes. Sickle cell anemia is due to a genetic mutation in the dna that encodes for the hemoglobin molecule. Thus, it is hereditary. Read more...
Sickle cell disease. Yes. For example, if both parents have sickle cell trait (each have one copy of a sickle beta-hemoglobin gene and one unaffected copy), they have a 25% chance of having a child with sickle cell disease, a 50% chance of the child having sickle cell trait, and a 25% chance of the child having completely normal hemoglobin (no trait or sickle cell disease). Read more...
Yes. it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. Read more...

Why is sickle cell anemia painful?

Poor circulation. In sickle cell disease red cell stick together and block circulation to extremity and other organ so it cause pain crisis. Read more...

How is sickle cell anemia detected?

Blood test. Every newborn baby undergoes "newborn screening" test before they are released from hospital. Most of abnormal hemoglobins, e.g. Hemoglobin s in sickle cell disease, are detected. Read more...

How dangerous is sickle cell anemia?

More info needed. Patients with sickle cell anemia have greater tendency for severe anemia and infection. Usually children have more difficulties. Sometimes frequent transfusion is needed to assist in crises, or to suppress sickle hemoglobin and decrease sickling issues which can be very painful. Hydroxyurea is used to help symptoms and to increase fetal hemoglobin, vaccinations, and antibiotics help. See MD. Read more...

What is the trend in sickle cell anemia?

Who will have it bad. The trend currently is trying to find out why some people have very little problems and others can be so troubled by this disease. In some, the disease will cause strokes, lung problems, leg ulcers etc. If we knew early on who would have it bad, maybe treatments could be given earlier to prevent these problems. But not everyone has it bad, so it is hard to know. Read more...