13 doctors weighed in:

My blood group is a- (negative) and I had anti-d with my first pregnancy. Will I need it again with my second?

13 doctors weighed in
Dr. Amy Herold
Obstetrics & Gynecology
2 doctors agree

In brief: Yes

You should have anti-d in your second pregnancy.
It will protect the baby in subsequent pregnancies from problems related to blood-type mismatch between mom and baby.

In brief: Yes

You should have anti-d in your second pregnancy.
It will protect the baby in subsequent pregnancies from problems related to blood-type mismatch between mom and baby.
Dr. Amy Herold
Dr. Amy Herold
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Dr. Padmavati Garvey
Obstetrics & Gynecology
1 doctor agrees

In brief: Yes

Yes you will need again since your blood type will not have changed.

In brief: Yes

Yes you will need again since your blood type will not have changed.
Dr. Padmavati Garvey
Dr. Padmavati Garvey
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Dr. Jaime Lopez
Obstetrics & Gynecology
1 doctor agrees

In brief: Yes

Your blood type never changes, so you will need anti-d in all of your pregnancies, even miscarriages, terminations, or ectopic pregnancy.
But your doctor will run blood tests first to be sure that you still require the anti-d.

In brief: Yes

Your blood type never changes, so you will need anti-d in all of your pregnancies, even miscarriages, terminations, or ectopic pregnancy.
But your doctor will run blood tests first to be sure that you still require the anti-d.
Dr. Jaime Lopez
Dr. Jaime Lopez
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Dr. Alysia Townsend
Obstetrics & Gynecology
1 doctor agrees

In brief: Most likely

Unless the confirmed father of the baby is also rh negative, proven by testing, you will continue to need Rhogam with each pregnancy.
The only exception is when you have already become rh sensitized, or have rh isoimmunization, in which case Rhogam or anti-d no longer is able prevent potential attack of fetal cells by maternal cells.

In brief: Most likely

Unless the confirmed father of the baby is also rh negative, proven by testing, you will continue to need Rhogam with each pregnancy.
The only exception is when you have already become rh sensitized, or have rh isoimmunization, in which case Rhogam or anti-d no longer is able prevent potential attack of fetal cells by maternal cells.
Dr. Alysia Townsend
Dr. Alysia Townsend
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Dr. Jeff Livingston
Obstetrics & Gynecology
1 doctor agrees

In brief: Yes

The Rhogam shot lasts for 14 weeks which is why it is given at 28 weeks to last through the end of pregnancy.
It needs to be repeated with each pregnancy. It also needs to be given after delivery if the baby is rh positive.

In brief: Yes

The Rhogam shot lasts for 14 weeks which is why it is given at 28 weeks to last through the end of pregnancy.
It needs to be repeated with each pregnancy. It also needs to be given after delivery if the baby is rh positive.
Dr. Jeff Livingston
Dr. Jeff Livingston
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Dr. Megan Bird
Obstetrics & Gynecology

In brief: Yes

You will need to get the Rhogam or anti-d injection with every pregnancy.
It is usually given at 28 weeks and sometimes again after delivery. If you have bleeding earlier in pregnancy, you may also need a shot.

In brief: Yes

You will need to get the Rhogam or anti-d injection with every pregnancy.
It is usually given at 28 weeks and sometimes again after delivery. If you have bleeding earlier in pregnancy, you may also need a shot.
Dr. Megan Bird
Dr. Megan Bird
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Dr. Craig Keathley
Obstetrics & Gynecology

In brief: Yes

Rhogam, anti-d antibody, is given to prevent rh neg women from forming their own antibodies to the d antigen if carrying an rh + fetus.
It is typically given at 28 weeks in order to protect during the highest risk time for exposure to fetal cells. This should be done during each pregnancy unless it is known with certainty that the father is also rh negative.

In brief: Yes

Rhogam, anti-d antibody, is given to prevent rh neg women from forming their own antibodies to the d antigen if carrying an rh + fetus.
It is typically given at 28 weeks in order to protect during the highest risk time for exposure to fetal cells. This should be done during each pregnancy unless it is known with certainty that the father is also rh negative.
Dr. Craig Keathley
Dr. Craig Keathley
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