Multiple ways. The sciatic nerve can be irritated because of a herniated disc, arthritis that results in tightening of the spinal canal, falls, injuries, or other rare reasons (tumors, infections). Anti-inflammatory medications, alternating heat/cold therapy, physical therapy (especially with traction) can be helpful to relieve sciatic pain.
Evaluate Low Back. If you are not improving have your doctor order a lumbar spine mri. Many times a herniated disc in the back can cause leg pain especially if you have not improved with the medications and physical therapy. If it is a herniated disc you may need evaluation from a spine specialist to determine what other options might be needed (injections, surgery, etc) to help reduce pain.
Many ways. Medications, interventions and procedures, physical therapy. See a pain doc.