3 doctors weighed in:

Pathophysiology of diabetes mellitus in pregnancy?

3 doctors weighed in
Dr. Douglas Lawson
Obstetrics & Gynecology
1 doctor agrees

In brief: Glucose intolerance

The short paragraph here doesn't give me alot to explain this, but basically pregnancy is a relatively glucose resistant state and the more times you are pregnant, the more likely you get gestational diabetes.
There are alterations in Insulin levels and Insulin resistance during the pregnancy. The typical american diet of high sugar processed foods doesn't help.

In brief: Glucose intolerance

The short paragraph here doesn't give me alot to explain this, but basically pregnancy is a relatively glucose resistant state and the more times you are pregnant, the more likely you get gestational diabetes.
There are alterations in Insulin levels and Insulin resistance during the pregnancy. The typical american diet of high sugar processed foods doesn't help.
Dr. Douglas Lawson
Dr. Douglas Lawson
Thank
Dr. Sudeshan Govender
Family Medicine

In brief: GDM

During early pregnancy, increases in estrogens, progestins, and other pregnancy-related hormones lead to lower glucose levels, promotion of fat deposition, delayed gastric emptying, and increased appetite.
As gestation progresses, however, postprandial glucose levels steadily increase as insulin sensitivity steadily decreases. For glucose control to be maintained in pregnancy, it is necessary for maternal insulin secretion to increase sufficiently to counteract the fall in insulin sensitivity. GDM occurs when there is insufficient insulin secretion to counteract the pregnancy-related decrease in insulin sensitivity.

In brief: GDM

During early pregnancy, increases in estrogens, progestins, and other pregnancy-related hormones lead to lower glucose levels, promotion of fat deposition, delayed gastric emptying, and increased appetite.
As gestation progresses, however, postprandial glucose levels steadily increase as insulin sensitivity steadily decreases. For glucose control to be maintained in pregnancy, it is necessary for maternal insulin secretion to increase sufficiently to counteract the fall in insulin sensitivity. GDM occurs when there is insufficient insulin secretion to counteract the pregnancy-related decrease in insulin sensitivity.
Dr. Sudeshan Govender
Dr. Sudeshan Govender
Thank