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Can you take cephalosporin if you are allergic to penicillin?

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Dr. Jeffrey Rosch
Internal Medicine - Allergy & Immunology

In brief: Pcn & Cehalosporins

The conventional number is 10% of penicillin allergic people are also allergic to cephalosporins, however the data is weak since the patient reported incidence of penicillin allergy may only be 10% accurate.
There are also 3 generations of cephalosporins and the "cross reactivity" may vary between them. There does seem to be a direct relationship between reaction severity and cross reactivity.

In brief: Pcn & Cehalosporins

The conventional number is 10% of penicillin allergic people are also allergic to cephalosporins, however the data is weak since the patient reported incidence of penicillin allergy may only be 10% accurate.
There are also 3 generations of cephalosporins and the "cross reactivity" may vary between them. There does seem to be a direct relationship between reaction severity and cross reactivity.
Dr. Jeffrey Rosch
Dr. Jeffrey Rosch
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