2 doctors weighed in:

Is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma, and pregnancy? Why?

2 doctors weighed in
Dr. Barbara Stark Baxter
Internal Medicine - Allergy & Immunology

In brief: Anti-cholinergic

Diphenhydramine's anticholinergic effects are to blame.
They cause it to aggravate increased intraocular pressure, and dry secretions in those having asthma attacks, making it hard to clear secretions. Here's a link: http://answers.Yahoo.Com/question/index?Qid=20090328145710aa3jfbq the link is wrong about pregnancy, though. It's category b, not c, for pregnancy and considered safer than other meds.

In brief: Anti-cholinergic

Diphenhydramine's anticholinergic effects are to blame.
They cause it to aggravate increased intraocular pressure, and dry secretions in those having asthma attacks, making it hard to clear secretions. Here's a link: http://answers.Yahoo.Com/question/index?Qid=20090328145710aa3jfbq the link is wrong about pregnancy, though. It's category b, not c, for pregnancy and considered safer than other meds.
Dr. Barbara Stark Baxter
Dr. Barbara Stark Baxter
Thank
Dr. Bud Kurwa
Ophthalmology

In brief: Yes

In patients with closable angles any dilating agent is dangerous as it can precipitate an attach of acute angle closure glaucoma.
Anti histamines are contraindicated. Best to see an ophthalmologist and get the angles checked. If they are indeed narrow and closable a laser procedure should be done to prevent a future attack.

In brief: Yes

In patients with closable angles any dilating agent is dangerous as it can precipitate an attach of acute angle closure glaucoma.
Anti histamines are contraindicated. Best to see an ophthalmologist and get the angles checked. If they are indeed narrow and closable a laser procedure should be done to prevent a future attack.
Dr. Bud Kurwa
Dr. Bud Kurwa
Thank
Get help from a real doctor now
Dr. Jonathan Jassey
Board Certified, Pediatrics
13 years in practice
1M people helped
Continue
108,000 doctors available
Read more answers from doctors