No surprise. Are you surprised if I say they all affect reproductive health in a bad way. Mild or even moderate alcohol use may have a negligible effect, but tobacco and marijuana are definitely harmful: the more you use, the worse the problem.
Different dangers. Too little is known about ecstasy for anybody to say. Right or wrong, marijuana is illegal and poses dangers to you, from job loss to making it impossible for you to get an organ transplant to cure your alcoholic liver disease. That alcohol ruins the lives of abusers & their families is obvious, and tobacco is the great avoidable life-shortener of the world. How about "none of the above" for you?