What is sickle cell disease?

Abnormal blood cells. Sickle cell disease occurs when there is an abnormal type of hemoglobin in blood cells. Thought to be a survivor advantage against malaria, when these cells have too little oxygen they collapse and get stuck in small vessels. This cuts off the blood supply to organs and causes severe pain. Sickle cell traits is when only half the genes code for the abnormal hemoglobin, usually not symptomatic.
A diseae of blood. Sickle cell disease is a disease cause by an abnormal hemoglobin protein carriedninside red cells. The protein becomes insoluble and causesthe red cells to stick in the blood stream and blocks blood flow.

Related Questions

What is sickle cell disease?

Common & inherited. Sickle cell disease is a very common inherited condition affecting hemoglobin & thus red blood cells, often leading to anemia as well as complications resulting from abnormal cell shape. Each (carrier) parent must have at least one gene for this condition in order for affected person to receive both to have actual disease. Check out http://ghr.Nlm.Nih.Gov/condition/sickle-cell-disease for info. Read more...
Red blood disorder. Autosomal recessive disorder when rbc's become rigid and cannot carry oxygen. The hemoglobin is abnormal. Also know as hbss vs hbas or trait. With low oxygen tension the beta chain of the hemoglobin molecule cannot carry oxygen properly and takes a different form-becomes sickle shaped, inelastic. They cannot pass through capillaries and lead to occlusion and ischemia. Rx transfusions, fluids. Read more...

Hi doctors, was just wondering what is a sickle cell disease?

Important gene... Sickle cell anemia is caused by a mutation in the gene that tells your body to make hemoglobin. Hemoglobin allows red blood cells to carry oxygen from your lungs to all parts of your body. In sickle cell anemia, the abnormal hemoglobin causes red blood cells to become rigid, sticky and misshapen. These abnormal red blood cells lead to the various symptoms of the disease. Read more...

What are the causes of sickle cell disease?

Inheritance. The sickle cell gene is a mutation in the way the hemoglobin molecule is formed.It takes a pair of sickle genes to cause the change.A single normal gene can cancel the abnormal gene effect. Parents with a single sickle cell gene will be asymptomatic. When a baby gets a sickle gene from both parents, the abnormal genes are expressed as SS disease. Read more...

What are the causes of sickle cell disease and what are some characteristics?

Genetic disease. Sickle cell disease means the patient inherited the gene for sickle cell disease from both mother and father. The disease is associated with anemia (low blood) and often some degree of jaundice (yellowness.) people with this problem are more likely to be ill with infections early in life and take antibiotics and receive special vaccinations, to help prevent infections. Read more...
Sickle cell disease. Genetic condition where the body makes stiff, sticky sickle-shaped red blood cells (rbc) instead of the flexible disk-shaped ones due to abnormal hemoglobin s. Sickle-shaped rbc get stuck in blood vessels interrupting blood flow & delivery of oxygen & food to organs, which causes pain, fatigue, organ damage and increases risk of infection. No cure but treatments are available. See hematologist. Read more...

What is the cause of sickle cell disease and trait?

Gene mutation. Sickle cell trait is caused bu the presence of a single mutation in the beta chain of human hemoglopin a gene. A mutation in one gene on one of a person's two beta globin genes results in sickle cell trait (sa hemoglobin) while the same mutation in both of a persons genes causes sickle cell anemia. (ss hemoglobin). The term trait means a carrier for the sickle cell mutation. Read more...

What is the treatment for sickle cell disease if any?

See below. Treatment for sickle cell anemia is usually aimed at avoiding crises, relieving symptoms and preventing complications. If you have sickle cell anemia, you'll need to make regular visits to your md to check your red cell count and monitor your health. Treatments may include medications to reduce pain and prevent complications, blood transfusions and supplemental oxygen, and bone marrow transplant. Read more...